Six1 is down-regulated in end-stage human dilated cardiomyopathy independently of Ezh2
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چکیده
منابع مشابه
Six1 is down‐regulated in end‐stage human dilated cardiomyopathy independently of Ezh2
BACKGROUND Recently, it was shown that a knock-out (KO) of the polycomb histone methyltransferase Ezh2 leads to cardiac hypertrophy in mice, which was driven by the homeodomain transcription factor Six1. Here, we analyzed the expression of Six1 and its regulating factor Ezh2 in cardiac tissue of patients with end-stage dilative cardiomyopathy (DCM). METHODS Tissue samples of patients with end...
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ژورنال
عنوان ژورنال: ESC Heart Failure
سال: 2014
ISSN: 2055-5822
DOI: 10.1002/ehf2.12017